Increased DNA methyltransferase expression in rhabdomyosarcomas
نویسندگان
چکیده
منابع مشابه
Suppression of Klotho expression by protein-bound uremic toxins is associated with increased DNA methyltransferase expression and DNA hypermethylation
The expression of the renoprotective antiaging gene Klotho is decreased in uremia. Recent studies suggest that Klotho may be a tumor suppressor, and its expression may be repressed by DNA hypermethylation in cancer cells. Here we investigated the effects and possible mechanisms by which Klotho expression is regulated during uremia in uninephrectomized B-6 mice given the uremic toxins indoxyl su...
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ژورنال
عنوان ژورنال: International Journal of Cancer
سال: 1999
ISSN: 0020-7136,1097-0215
DOI: 10.1002/(sici)1097-0215(19990924)83:1<10::aid-ijc3>3.0.co;2-f